Barbiturates

Barbiturate drugs are a class of sedative-hypnotic medications that depress the central nervous system, producing effects ranging from mild sedation to deep anesthesia. They work by enhancing the action of gamma-aminobutyric acid (GABA) at GABA-A receptors, similar to benzodiazepines but with a higher risk of overdose and dependence. Barbiturates were once widely used to treat anxiety, insomnia, and seizures but have primarily been replaced by safer alternatives like benzodiazepines.

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