TETRODOTOXIN from Fugu fish
Buy TETRODOTOXIN from Fugu fish
TTX ; Spheroidene; Maculotoxin; Tarichatoxin; Tetrodotoxin; Tétrodotoxine; Fugu poison
Tetrodotoxin is a highly specific Na+ channel blocker in excitable tissues, purified from organs of fish of the Tetraodon genus (Takifugu oblongus).
Molecular formula: C11H17N3O8
Chemical structure: Click on the picture on the left.
Molecular weight: 319.27 Da
Purity: ≥ 98%
Biological Activity: Buy TETRODOTOXIN from Fugu fish Tetrodotoxin is a Na+ channels blocker.
Tetrodotoxin (TTX) binds reversibly to site 1 of the fast voltage-gated sodium channel located at the extracellular pore opening of the ion channel. The binding of a molecule to this site temporarily disables the ion channel.
TTX is used as a chemical tool in channel characterization and in fundamental studies of channel function.
TTX is a valuable agent for the silencing of neural activity within a cell culture.
KD (cardiac myocytes in rats): 0.8 nM.
10-8 M block nervous system; 10-5 M block heart muscle.
ED50 = 3.7 nM.
Identification: Buy TETRODOTOXIN from Fugu fish
- PRODUCT ID: L8503-TETRODOTOXIN (Citrate free)
- CAS Number : 4368-28-9
- T3DB : T3D2484
- PubChem CID: 16759596
- EC Number: 224-458-8
- InChI Key: CFMYXEVWODSLAX-HUILCFQTSA-N
- RTECS Number: IO1450000