Description
ELAPITOXIN-Ls2a (Alpha-) from Laticauda semifasciata Ls III ;
BUY ELAPITOXIN-Ls2a (Alpha-) from Laticauda semifasciata Ls III
Main Features: α-Elapitoxin-Ls2a
Alpha-Elapitoxin-Ls2a is a 66-amino acid peptide with 5 disulfide bridges, from Laticauda semifasciata snake venom. It is an antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction with a weaker affinity to the receptor than Erabutoxins a and b. Higher chemical the world exclusive source of this toxin.
Amino-Acid sequence: Click on the picture on the left.
Molecular weight : 7,229 Da
Purity: Salt-free, a freeze-dried preparation
Homogeneous (CM-cellulose & gel-chromatography)
Biological Activity: Alpha-Elapitoxin-Ls2a is a nicotinic receptor antagonist, with a reversible binding to the receptor (its affinity is 1/40th that of Erabutoxin b).
Its binding to the acetylcholine receptors of Torpedo marmorata electric organs:
Kd = 1.6 x 10-9 M.
Identification :
- PRODUCT ID: L8112-Alpha-Elapitoxin-Ls2a
- CAS Number : 75433-28-2
- UNIPROT ID: P01379
- EC Number:
- InChI Key:
- RTECS Number:
| Name | ELAPITOXIN-Ls2a (Alpha-) |
| Molecular formula | |
| Description | It is an antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction with a weaker affinity to the receptor than Erabutoxins a and b
|
| Biological activity | It is a nicotinic receptor antagonist, with a reversible binding to the receptor (its affinity is 1/40th that of Erabutoxin b). It is binding to the acetylcholine receptors of Torpedo marmorata electric organs: Kd = 1.6 x 10-9 M. |
ELAPITOXIN-Ls2a (Alpha-) from Laticauda semifasciata Ls III – For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Reviews
There are no reviews yet.