ELAPITOXIN-Ls2a (Alpha-) from Laticauda semifasciata Ls III ; α-Elapitoxin-Ls2a

ELAPITOXIN-Ls2a (Alpha-) from Laticauda semifasciata Ls III ; α-Elapitoxin-Ls2a

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Description

ELAPITOXIN-Ls2a (Alpha-) from Laticauda semifasciata Ls III ;

BUY ELAPITOXIN-Ls2a (Alpha-) from Laticauda semifasciata Ls III

Main Features : α-Elapitoxin-Ls2a

Alpha-Elapitoxin-Ls2a is a 66-amino acid peptide with 5 disulfide bridges, from Laticauda semifasciata snake venom. It is an antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction with a weaker affinity to the receptor than Erabutoxins a and b. Higher chemical the world exclusive source of this toxin.

Amino-Acid sequence: Click on the picture on the left.
Molecular weight : 7,229 Da

Purity: Salt-free, a freeze-dried preparation
Homogeneous (CM-cellulose & gel-chromatography)

Biological Activity: Alpha-Elapitoxin-Ls2a is a nicotinic receptor antagonist, with a reversible binding to the receptor (its affinity is 1/40th that of Erabutoxin b).
Its binding to the acetylcholine receptors of Torpedo marmorata electric organs:
Kd = 1.6 x 10-9 M.

Identification :

  1. PRODUCT ID: L8112-Alpha-Elapitoxin-Ls2a
  2. CAS Number : 75433-28-2
  3. UNIPROT ID: P01379
  4. EC Number:
  5. InChI Key:
  6. RTECS Number:
Name ELAPITOXIN-Ls2a (Alpha-) 
Molecular formula
Description It is an antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction with a weaker affinity to the receptor than Erabutoxins a and b


66-amino acid peptide with 5 disulfide bridges, from Laticauda semifasciata snake venom

Biological activity It is a nicotinic receptor antagonist, with a reversible binding to the receptor (its affinity is 1/40th that of Erabutoxin b).
It is binding to the acetylcholine receptors of Torpedo marmorata electric organs:
Kd = 1.6 x 10-9 M.

ELAPITOXIN-Ls2a (Alpha-) from Laticauda semifasciata Ls III – For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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